The importance of stem cell competition for low-dose and low-dose-rate radiation effects
نویسندگان
چکیده
منابع مشابه
Scientific Risk Estimation on Health Effects of Low Dose and Low Dose-Rate Radiation - An Overview
Estimation of the scientific risks of high dose radiation has been successfully quantified by many studies using several different approaches. However, the risk for low and low dose-rate radiation is obscure because of a lack of evidence. This risk is currently estimated by extrapolating the radiation response at high doses into low dose ranges for practical purposes. Recent challenges to exami...
متن کاملNew insight into cancer risks from radiation exposure of low dose and low dose rate
For example, the Chernobyl accident caused the deposition of radioisotopes over wide areas of the Northern Hemisphere, in particular in Europe ( Atlas of Caesium Deposition on Europe after the Chernobyl Accident, 1998), followed by protracted chronic exposure of some millions of people to external and internal radiation. You can see the map of radioactive contamination of Europe after the Chern...
متن کاملEffects of Low-Dose Ionising Radiation
Recent years there have been a number of discussions about the magnitude of the health risks resulting from the exposure to low levels of ionising radiation mainly within the American Health Physics Society, the French Academy of Sciences and the Canadian Radiation Protection Association. Essentially, the debate has centred on the question of linearity, i.e., whether to assume that the probabil...
متن کاملLow-dose or low-dose-rate ionizing radiation–induced bioeffects in animal models
Animal experimental studies indicate that acute or chronic low-dose ionizing radiation (LDIR) (≤100 mSv) or low-dose-rate ionizing radiation (LDRIR) (<6 mSv/h) exposures may be harmful. It induces genetic and epigenetic changes and is associated with a range of physiological disturbances that includes altered immune system, abnormal brain development with resultant cognitive impairment, catarac...
متن کاملDose-rate effects and dose and dose-rate effectiveness factor on frequencies of chromosome aberrations in splenic lymphocytes from mice continuously exposed to low-dose-rate gamma-radiation.
Dose-rate effects on chromosome aberrations in the low-dose-rate range have not been evaluated previously. The incidences of chromosome aberrations were analysed in splenic lymphocytes from female specific pathogen-free (SPF) C3H mice that were continuously irradiated with low- or medium-dose-rate (LDR, MDR) (137)Cs γ rays from 56 days of age to evaluate the dose-rate effects. The dose-response...
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ژورنال
عنوان ژورنال: Journal of the Atomic Energy Society of Japan
سال: 2019
ISSN: 1882-2606,2433-7285
DOI: 10.3327/jaesjb.61.11_788